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Multiple Sclerosis (MS) is a disorder occurring in the central nervous system where the immune system attacks the myelin sheath of neurons. It is a progressive disease which is caused due to damage in the fatty layer surrounding the axons, interrupting electrical impulses. Symptoms of the disease include extreme fatigue, impaired vision, muscle spasms, weak bladder control, memory loss, difficulty in hand-eye coordination and partial or complete paralysis.
Since there is no treatment for MS yet, it is commonly managed through medications and alternate ways in the relapse stages. Lion's Mane, which have shown very promising results in other neurological diseases, have also been researched in the context of MS.
Lion’s Mane mushroom has proven to stimulate a decrease in beta-amyloid plaques; which are proteins that develop in the myelin sheath and disrupt neurotransmission. The study involved injecting rats with neurotoxin peptides which induces plaque formation. After treatments with Lion’s Mane in their diets, the rats improved in their cognitive abilities and developed new neurons. (1)
Lion's Mane has the power to stimulate synthesis of Nerve Growth Factor (NGF) protein that promotes maintenance and regeneration of nerve cells in both, the central and peripheral nervous systems. NGF protein also plays an important role in stimulating the production of myelin sheath around cells. Lion's Mane studies have found NGF to protect oligodenrocytes, which are myelin producing cells; and the production of Brain Derived Neurotrophic Factor (BDNF). (2)
Other animal and in vitro studies have shown the ability of Lion’s Mane to promote nerve growth and myelin sheath production and stimulating it at an increased pace. This has proven to be helpful in managing and recovering from a relapse stage in Multiple Sclerosis. (3)
Pharmaceutical drugs are not always the best solution to MS patients. Costs are increasingly high and side effects can be severe. Most approved medications are used to slow disease progression, but they do not cure the condition.
Mógū aims to raise awareness about the therapeutic potential of natural medicines like Lion's Mane mushroom, calling for all consumers to learn more about them in order to promote a less-expensive, less-toxic support to traditional MS drugs.
Click on other conditions in this page to continue exploring studies done on Lion's Mane: