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In a human clinical trial of 30 individuals (subjects being 50-80 year old Japanese men and women diagnosed with mild cognitive impairment) were randomized into two 15 person groups. The treatment group was given 3g/day of Lion's Mane as tablets for 16 weeks. At weeks 8, 12 and 16 of the trial, the treatment group showed significantly greater scores on the cognitive function scale compared with the placebo group. Improvements in independence and in their ability to perform normal tasks were also observed. The Lion's Mane group's scores increased significantly compared to the placebo group with the duration of intake, but at week 4 after the termination of the 16 weeks intake, the scores decreased significantly. The results obtained in this study suggest that Lion's Mane is effective in improving mild cognitive impairment, with increasing results during consistent use.
A strong correlation comes from the mushrooms ability to promote growth of neurogenic growth factor, but continuous use is needed to maintain the improvement. Toxic effects were not found on extensive blood tests and no serious side effects were reported.
Mógū recommends mushroom enthusiasts to continue the consumption of Lion's Mane (as recommended with other medicinal mushrooms) for a prolonged period of time to experience the gradual effects of fungi. Remember that all mushrooms are magic, and including different species of medicinal mushrooms in your daily diet is what Mógū is here to promote.
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